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Toxicological Profile Information
Sheet
Background
By Congressional mandate, the Agency for Toxic Substances and Disease
Registry (ATSDR) produces "toxicological profiles" for hazardous substances
found at National Priorities List (NPL) sites. These hazardous substances
are ranked based on frequency of occurrence at NPL sites, toxicity, and
potential for human exposure. Toxicological profiles are developed from
a priority list of 275 substances. ATSDR also prepares toxicological profiles
for the Department of Defense (DOD) and the Department of Energy (DOE)
on substances related to federal sites.
So far, 275 toxicological profiles have been published or are under development
as "finals" or "drafts for public comment"; 260 profiles
were published as finals; 111 profiles have been updated. Currently, 8
profiles are being revised based on public comments received and 1 profile
is being developed as public comment draft. These profiles cover more
than 250 substances.
Toxicological profiles are developed in two stages:
(1) DRAFTS: The toxicological profiles are first produced as drafts.
ATSDR announces in the Federal Register the release of these draft
profiles for a 90-day public comment period. Request draft toxicological
profiles from ATSDR's Division of Toxicology.
(2) FINALS: After the 90-day comment period, ATSDR considers incorporating
all comments into the documents. ATSDR finalizes the profiles and the
National Technical Information Service (NTIS) distributes them.
ATSDR's toxicological mailing list
Congress requires ATSDR (1) to provide toxicological profiles to state
health and environmental agencies and (2) to make them available to other
interested parties. The Division of Toxicology (DT) has a mailing list,
which is updated and verified yearly, of groups and individuals who get
free copies of both draft and final profiles; these include health professionals
at federal, state, and local levels; academicians; nonprofit/environmental
groups; members of the public involved with Superfund sites; and parties
with special needs (considered case-by-case).
If you don't qualify for free copies, you may request final profiles
from NTIS for a fee.
How to contact NTIS
NTIS distributes finalized toxicological profiles for a fee. For more
information, contact
National Technical Information Service 
5285 Port Royal Road
Springfield, Virginia 22161
1-800-553 6847 or 703-605-6000
Web site: http://www.ntis.gov
Additional Resources:
- ATSDR ToxProfiles 2004™ CD-ROM - The toxicological profiles
are also available as a complete set on CD-ROM.
- Public Health Statements (PHS) - The PHS are a series of summaries
about hazardous substances taken from Chapter One of their respective
ATSDR Toxicological Profiles.
- ATSDR ToxFAQs™ - The ToxFAQs™ are a series of 2-page
fact sheets about hazardous substances.
To request a copy of the ToxProfiles™ CD-ROM, PHS, or ToxFAQsTM
call 404-498-0261 or email your request to atsdric@cdc.gov.
For more information on the above listed publications, write
Division of Toxicology, Agency for Toxic Substances and Disease
Registry
1600 Clifton Road, Mailstop F-32, Atlanta, GA 30333
For more information 24 hours/day
You may call the ATSDR toll free number at 1-888-42-ATSDR (1-888-422-8737)
to get 24-hour recorded information about Division of Toxicology programs.
This phone number includes options to be transferred to ATSDR personnel
for technical assistance.
ATSDR Internet home page via World Wide Web: http://www.atsdr.cdc.gov
The profiles, public health statements, ToxFAQs™ and other
information are available on the Internet.
FINALIZED TOXICOLOGICAL PROFILES
Finalized toxicological profiles by chemical with NTIS order number
(Updates are in bold. Asterisks denote tox profiles funded by the Department
of Defense)
-A-
-B-
-C-
-D-
- 4,4'-DDT,
DDE,DDD (Update) (PB2003-100137)
- Diazinon
(PB/97/121107/AS)
- Dibenzo(a,h)anthracene
(PB/90/247636/AS)
- Dibromochloropropane
(PB/93/110906/AS)
- 1,2-Dibromoethane
(PB/93/110740/AS)
- 1,4-Dichlorobenzene
(Update) (PB/99/121972)
- 3,3'-Dichlorobenzidine
(Update) (PB/99/121980)
- 1,1-Dichloroethane
(PB/91/180539/AS)
- 1,2-Dichloroethane
(Update) (PB/2001/109103/AS)
- 1,1-Dichloroethene
(Update) (PB/95/100152/AS)
- cis-, trans-
1,2-Dichloroethene (Update)(PB/97/121081/AS)
- 2,4-Dichlorophenol
(PB/93/110757/AS)
- 1,2-Dichloropropane
(PB/90/182122/AS)
- 1,3-Dichloropropene
(PB/93/110765/AS)
- Dichlorvos
(PB/98/101124/AS)
- Di(2-ethylhexyl)phthalate
(Update) (PB2003-100138)
- Diethyl phthalate
(PB/95/264214/AS) *
- Diisopropylmethylphosphonate
(PB/99/102535/AS) *
- Di-n-butyl
phthalate (Update) (PB/2001/109104/AS)
- 1,3-Dinitrobenzene/1,3,5-Trinitrobenzene
(PB/95/264289/AS)*
- Dinitrocresols
(PB/95/264321)
- Dinitrophenols
(PB/95/264339)
- 2,4- &
2,6-Dinitrotoluene (Update) (PB/99/122004)
- Di-n-octylphthalate
(PB/98/101033/AS) *
- Dioxin (Update)
(PB/99/121998)
- 1,2-Diphenylhydrazine
(PB/91/180356/AS)
- Disulfoton
(PB/95/264347)
-E-
-F-
-G-
None Available
-H-
-I-
-J-
-K-
None Available
-L-
- Lead
(Update) (PB/99/166704)
-M-
-N-
-O-
-P-
- Pentachlorophenol
(Update) (PB/2001/109106/AS)
- Phenol
(Update) (PB/99/122012)
- Plutonium
(PB/91/180406/AS)
- Polybrominated biphenyls /polybrominated
diphenyl ethers (Update) (PB2004-107334)
- Polychlorinated
biphenyls: (Update) (PB/2000/108027)
Aroclors -1260,-1254, -1248, -1242, -1232, -1221, and -1016
- Polycyclic
aromatic hydrocarbons: (Update) (PB/95/264370)
Acenaphthene, Acenaphthylene, Anthracene, Benzo(a)anthracene, Benzo(a)pyrene,
Benzo(b)fluoranthene, Benzo(g,h,i)perylene, Benzo(k)fluoranthene, Chrysene,
Dibenzo(a,h)anthracene, Fluoranthene, Fluorene, Indeno(1,2,3-cd)pyrene,
Phenanthrene, Pyrene
- Pyrethrins and Pyrethroids (PB2004-100004)
- Pyridine
(PB/93/110831/AS)
-Q-
None Available
-R-
-S-
-T-
- 2,3,7,8-Tetrachlorodibenzo-p-dioxin (Update)
(PB/89/214522/AS)
- 1,1,2,2-Tetrachloroethane
(Update) (PB/97/121099/AS)
- Tetrachloroethylene
(Update) (PB/98/101181/AS)
- Tetryl
(PB/95/264271/AS) *
- Thallium
(PB/93/110856/AS)
- Thorium
(PB/91/180448/AS)
- Tin
(PB/93/110864/AS)
- Titanium tetrachloride
(PB/98/101082/AS) *
- Toluene
(Update) (PB/2000/108028)
- Toxaphene
(Update) (PB/97/121057/AS)
- Total Petroleum
Hydrocarbons (PB/99/163370) *
- 1,1,1-Trichloroethane
(Update) (PB/95/264396)
- 1,1,2-Trichloroethane
(PB/90/196411/AS)
- Trichloroethylene
(Update) (PB/98/101165/AS)
- 2,4,6-Trichlorophenol
(PB/91/181545/AS)
- 1,2,3-Trichloropropane
(PB/93/110872/AS)
- 2,4,6-Trinitrotoluene
(PB/95/264297/AS) *
-U-
-V-
-W-
-X-
-Y-
None Available
-Z-
- Zinc
(Update) (PB/95/100236/AS)
Toxicological
profiles under development as "draft for public comment"
--
CERCLA Set 17
Bromoform
(Update)
Carbon
tetrachloride (Update)
Hexachlorocyclohexanes
(Update)
Naphthalene
(Update)
Nickel
(Update)
Tin
(Update)
Tungsten
Zinc
(Update)
* The toxicological
profile for perchlorates is on a modified schedule.
The public comment period has ended and the profiles will be revised
based on relevant public comments.
Toxicological
profiles under development as "draft for public comment"
--
CERCLA Set 18
Cyanide
(Update)
Dichlorobenzenes
(Update)
1,4-Dioxane
Hydrogen
sulfide (Update)
1,1,1,-Trichloroethane
(Update)
Vinyl
chloride (Update)
The CERCLA Set 18 profiles were made available for public comment on
October 17, 2004. The public comment period will end on February 23, 2005.
Editor's note: CERCLA is the Comprehensive Environmental Response,
Compensation, and Liability Act of 1980 (Superfund).
List updated on December 8, 2004
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